5th International Conference on Neuroscience and Mental Health

The global population is ageing at an unprecedented rate, and with this demographic transformation comes an exponential rise in the burden of age-related neurological conditions, most prominently dementia, Alzheimer's disease, Parkinson's disease dementia, and vascular cognitive impairment. This session brings together neurologists, geriatricians, neuropsychiatrists, research scientists, and healthcare policymakers to examine the most significant advances in our understanding and management of these devastating conditions. With tens of millions of people currently living with dementia worldwide, and the number projected to triple by 2050, this session has never been more scientifically important or socially urgent.

The search for disease-modifying therapies for Alzheimer's disease has long been one of the most challenging quests in medicine, but recent years have brought genuine progress, and this session will present the most up-to-date clinical trial evidence for emerging treatments, including anti-amyloid and anti-tau immunotherapies. Participants will engage with cutting-edge research on the early detection of dementia through blood-based biomarkers, digital cognitive screening, advanced neuroimaging, and genetic risk profiling, tools that are bringing the possibility of pre-symptomatic intervention progressively closer to clinical reality.

Beyond pharmacological treatment, this session will address the holistic care needs of people living with dementia, including cognitive stimulation therapy, non-pharmacological interventions for behavioural and psychological symptoms, caregiver support programmes, and end-of-life care considerations. The science of healthy brain ageing will also be explored, with presentations on lifestyle factors, including physical activity, nutrition, sleep, cognitive engagement, and social connection, that are proven to reduce dementia risk and promote cognitive resilience across the lifespan. This session is an essential platform for all professionals committed to improving the lives of older adults with neurological conditions and their families.

Key Topics:

• Alzheimer's Disease: Pathophysiology, amyloid and tau biology, disease-modifying therapy clinical trials, and biomarker advances.
• Vascular Dementia: Cerebrovascular risk factors, neuroimaging findings, and the overlap between vascular disease and neurodegenerative dementia.
• Early Detection of Dementia: Blood-based biomarkers, digital cognitive assessment, neuroimaging, and genetic screening for preclinical dementia detection.
• Lewy Body and Frontotemporal Dementia: Clinical features, differential diagnosis, pathophysiology, and management of non-Alzheimer's dementias.
• Disease-Modifying Therapies: Latest clinical trial evidence for anti-amyloid, anti-tau, and other disease-modifying approaches to Alzheimer's treatment.
• Non-Pharmacological Interventions: Evidence for cognitive stimulation, music therapy, physical activity, and other non-drug approaches to dementia management.
• Caregiver Burden and Support: The psychological, physical, and social impact of caregiving, and effective support programmes for family caregivers.
• Healthy Brain Ageing: Lifestyle factors, risk reduction strategies, and the neuroscience of cognitive resilience in the ageing population.